专栏作家凯莉(萨拉·杰西卡·帕克 Sarah Jessica Parker 饰)、公关经理萨曼莎(金·卡特拉尔 Kim Cattrall 饰)、律师米兰达(辛西娅·尼克松 Cynthia Nixon 饰)还有理想主义者夏洛特(克里斯汀·戴维斯 Kristin Davis 饰)是生活在纽约曼哈顿中的四位时尚女性。她们之间有着坚固的友谊,却有着各自的个性。不同的性格带领她们走向不尽相同的生活方式,她们自知自己已不再年轻,周旋在各式男人身边寻找情欲。她们不过是想在那个忙碌且充满欲望诱惑的城市里,努力寻找自己的真爱。现实让她们一次次落空,借着友谊的力量继续向着自己的理想往前走。
Wayo is accepted at the Kantaphat University, in the Faculty of Sciences; in the same institution he studies, Phana, a second-year boy he has always been in love with, though he never managed to talk to him. When Wayo has the chance to become the moon of his faculty, the two will begin to spend time together because Phana himself has been the moon of the medical school the previous year and must supervise the freshmen participating in the competition. Despite initially the strong character of Phana makes it difficult for Wayo any more simple interaction, the two slowly get closer and closer. So, Wayo began to visit friends of Phana, Beam and Kit; it is the latter who suddenly falls in love with Ming, Wayo's best friend, who begins to court him despite his initial haste.